منابع مشابه
A case of 5-fluorouracil induced encephalopathy.
Patients with reduced dihydropyrimidine dehydrogenase (DPD) activity are at risk for experiencing serious adverse effects following 5-fluorouracil (5-FU) based chemotherapy. Neurotoxicity is considered an extremely rare side effect of 5-FU. We report here on an unusual case of 5-FU induced encephalopathy. A 38-year-old woman with advanced gastric carcinoma was treated with adjuvant chemotherapy...
متن کاملAcute hyperammonemic encephalopathy after 5-fluorouracil based chemotherapy.
5-Fluorouracil (5-FU) based chemotherapy has been commonly used to treat metastatic or advanced colon cancer as an adjuvant chemotherapy. Although the side effects of 5-FU such as gastrointestinal problems and neutropenia and thrombocytopenia are common, not many cases of 5-FU related encephalopathy are reported. Hyperammonemic encephalopathy is a rare central nervous system toxicity following ...
متن کامل5-Fluorouracil–induced Encephalopathy in a 51-year-old Man
A case of hyperammonaemic encephalopathy that developed during the administration of a widely used chemotherapy regimen is reported in a 51-year-old man. 5-Fluorouracil was considered to be the causative agent. Although encephalopathy is a rare toxic effect of 5-fluorouracil, this case illustrates a serious and potentially life-threatening complication during a chemotherapy regimen using 5-fluo...
متن کاملCase Reports Intermediate Dose 5-Fluorouracil-Induced Encephalopathy
As anacute neurotoxicity, high dose5-fluorouracil (5-FU)-induced encephalopathy iswell-known, but encephalopathy associated with lower dose is rarely reported. Here, we report a case of a male with anal cancer who was treated with 5-FU 1000 mg/m, continuous infusion for 5 days q4 weeks. At the second and the fourth cycles of chemotherapy, sudden confusion, cognitive dysfunction and disorientati...
متن کاملAtypical diffusion-restricted lesion in 5-Fluorouracil encephalopathy.
Central nervous system toxicity of 5-FU could show various manifestations, such as decreased alertness, disorientation, and agitation. It is generally accepted that lesions of 5-FU encephalopathy are mainly in the deep cerebral white matter and corpus callosum on MR imaging. Here we describe a case of 5-FU encephalopathy in gastric cancer with an atypical reversible diffusion-restricted lesion ...
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ژورنال
عنوان ژورنال: Cleveland Clinic Journal of Medicine
سال: 2020
ISSN: 0891-1150,1939-2869
DOI: 10.3949/ccjm.87a.19126